Now, for DIY-ing pepper spray, the best way is to extract the active chemical in chilies (capsaicin) by using a solvent. We will be extracting capsaicin from chillies using acetone solvent extraction.… Don’t worry, the procedure is fairly easy and it doesn’t require complicated chemistry skills or knowledge, but we’ll get back to that in a moment. Hence, making your own pepper spray is not such a bad idea after all. While youtube videos of DIY pepper sprays make it appear like that, a home-made pepper spray is far more effective if you do it the right way. Stir 2 tablespoons of powdered red pepper into 1 … : In this instructable, I will be showing you how to make your own Pepper spray at home! Step 1: Factors to Consider in Making a Home-made Pepper Spray. I often refer to it as "pepper soup." How to Make Pepper Spray at Home! You can make your own inexpensive pepper-based critter repellent for the garden, courtesy of the environmentally safe hot pepper. Commercial Pepper spray is made using capsaicin, the active chemical in chillies. Most recipes for DIY pepper spray call for several ingredients usually found at home. The first clear danger of homemade self-defense spray is the composition. Most DIY videos will instruct you to use any pepper you think is spicy enough, mash it and pour it into some cheap cologne spray bottle.