PCSK9 inhibitors are expected to work synergistically with statins. Drug images are also included. “Part of the reason is that the body compensates by increasing levels of PCSK9,” he explains. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Repatha (evolocumab) is a PCSK9 inhibitor used to treat hypercholesterolemia (high cholesterol). It is meant to be representative but may not accurately reflect the actual # of prescriptions written to treat a specific condition. Drug information provided by: IBM Micromedex. Includes Repatha side effects, interactions and indications. If you are having difficulty accessing this website, please email us at ada@goodrx.com so that we can provide you with the services you require through alternative means. To find your exact price, please contact the pharmacy (and note that the pharmacy will need to process the information shown on your coupon to confirm the price.). This chart is created by aggregating the total number of claims for the drugs in this class divided by the # of drugs with a specific indication. Repatha ; Descriptions. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. GoodRx gathers prices and discounts from multiple sources, including published price lists, drug manufacturers, claims information and data provided to us by pharmacies. PCSK9 inhibitors These medications offer an alternative for those who can’t take statins. Right now, there are two FDA-approved medications: alirocumab (Praluent) and evolocumab ( Repatha ). PCSK9 inhibitors are a new class of drugs that lower LDL, or “bad,” cholesterol. How PCSK9 inhibitors lower Lp(a) concentrations is unknown and warrants further research. Two PCSK9 inhibitors are currently available in the UK and others are in the process of being developed. GoodRx provides no warranty for any pricing data or other information. The research study is a wholesome collection of primary and secondary data collected and analysed from valuable information sources. The ones are can be used in the UK are Evolocumab and Alirocumab. PCSK9 Inhibitors: Dosing, Uses, Side Effects, Interactions, Patient Handouts, Pricing and more from Medscape Reference. The study on the global PCSK9 Inhibitors Market for all relevant companies dealing with the PCSK9 Inhibitors Market and related profiles include data in quantitative terms, product portfolio, and business strategy along with active tracking of recent developments. They work by helping to reduce the amount of … GoodRx works to make its website accessible to all, including those with disabilities. Statins are available in brand-name and generic forms. Note: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Brand names: Repatha Drug class(es): PCSK9 inhibitors Evolocumab systemic is used in the treatment of: Cardiovascular Risk Reduction; High Cholesterol; High Cholesterol, Familial Heterozygous; High Cholesterol, Familial Homozygous; See Also → Search the entire Drugs.com site for evolocumab. PCSK9 inhibitors may provide another treatment option … EVOLOCUMAB is known as a PCSK9 inhibitor. Some drugs are prescribed for multiple conditions. The PCSK9 inhibitor blocks the PCSK9 enzyme, resulting in more LDL receptors available to remove LDL from the blood, which produces in a decrease in LDL blood levels. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Proprotein convertase subtilisin/kexin type 9 (PCSK9) is an enzyme involved in the regulation of LDL receptors and LDL cholesterol. Evolocumab injection is used together with a proper diet, alone or together with other medicines (eg, ezetimibe, statins), to treat patients with heterozygous familial hypercholesterolemia (also called primary hyperlipidemia) or with homozygous familial hypercholesterolemia (HoFH), who need … PCSK9 Inhibitors. 6 Plasma PCSK9 concentrations are raised by statins and this could attenuate the effect of these drugs. They are not yet licensed for use. For You News & Perspective ... More than 7100 monographs are provided for prescription and over-the-counter drugs, as well as for corresponding brand-name drugs, herbals, and supplements. It is used to lower the level of, Alirocumab is a PCSK9 inhibitor. 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